Science writer and independent researcher specialising in natural compound pharmacology and translational oncology. Tracking EBC-46 (tigilanol tiglate) and Blushwood berry extract since 2019.
How tincture concentration varies across blushwood berry extract supplements on the market, and what user reports say about strength, dosing, and consistency.
How insect herbivory pressure has shaped seed defensive chemistry in Fontainea picrosperma — and why blushwood berries concentrate tigilanol tiglate in their seed coat.
How dose-limiting toxicity is defined and adjudicated in Phase I oncology trials of tigilanol tiglate, and what these definitions mean for trial readouts.
How ferroptosis — iron-catalysed lipid peroxidation cell death — interacts with EBC-46 / tigilanol tiglate signalling and the surrounding research literature.
How Argentina's ANMAT regulates botanical dietary supplements and what classification pathway applies to blushwood berry extract products in 2026.
consumer
Practical storage considerations for blushwood berry extract supplements — bottle materials, light, temperature, expiry dates, and what user reports suggest about real-world shelf life.
Botany
A look at the floral biology, pollinators, and reproductive ecology of Fontainea picrosperma — the small rainforest tree that produces blushwood berry, the source of EBC-46.
trials
How progression-free survival is defined, why it matters as a clinical trial endpoint, and how it has appeared in the published tigilanol tiglate (EBC-46) human trial literature.
mechanism
How endoplasmic reticulum stress and the unfolded protein response intersect with PKC signalling, and what published research suggests about tigilanol tiglate's convergence with these pathways.
Regulatory
How South Korea's Ministry of Food and Drug Safety regulates botanical extracts and what the Health Functional Foods (HFF) framework means for EBC-46 supplement availability in Korea.
Consumer Reports
A neutral pattern review of self-reported energy and wellbeing observations from EBC-46 supplement users — what people commonly describe, methodological limits, and how to evaluate such reports.
Botany
How canopy structure modulates the light microclimate around Fontainea picrosperma trees and what that means for fruit set, seed development, and cultivation planning.